The NEP 2020 underscores the importance of inclusivity as a cornerstone for transforming education in India. To achieve this vision, in-service teacher training becomes a critical lever for change, equipping educators with the necessary skills, knowledge, and strategies to create inclusive classrooms. This paper examines the role of in-service teacher training in implementing the NEP 2020 guidelines for inclusive education. It highlights the need for pedagogical shifts and current gaps in India’s teacher training landscape. Drawing on successful case studies from Indian and international practices, this review explores effective models of professional development, such as collaborative workshops, mentorship programs, and blended learning approaches, to empower teachers. It provides recommendations for designing context-specific training modules, strengthening policy frameworks, and establishing robust monitoring systems. By aligning in-service teacher training with NEP 2020 guidelines, India can make significant progress in creating inclusive classrooms that cater to the diverse needs of all students.